Thyroid Hormone Therapy

It is estimated that more than half of all people who are affected by thyroid disease are not aware of their condition even though patients may have many of the following symptoms of hypothyroidism which include:

  • Weight gain
  • Cold and heat intolerance (cold hands and feet)
  • Fatigue
  • Slowed metabolism
  • Memory and concentration impairment
  • Fluid retention
  • Constipation
  • Dry skin and/or hair
  • Depression
  • Low sexual desire
  • Headaches, Migraines
  • Irregular menstrual cycles
  • PMS
  • Enlarged tongue
  • Swollen neck
  • Deep voice
  • Infertility
  • Hypoglycemia (low blood sugar)

Patients may have some or most of the above symptoms, but may not be diagnosed for years!

Thyroid Hormone exists in 2 major forms:

  • (T3) Triiodothyronine – is the active form of thyroid hormone. The thyroid gland produces about 20 % of T3, the rest is produced in various tissues in the body through the conversion of T4 when more T3 is needed.
  • (T4) Thyroxine – is the inactive form produced exclusively by the thyroid gland.

In today’s society, most people are only treated with synthetic T4, although both T4 and T3 are secreted by the human thyroid gland. Some studies suggest that replacement therapy with T4 alone does not ensure normal thyroid levels in all tissues.

Some of the hypothyroid patients treated with T4 alone still remain symptomatic. A combination of T4 and T3 may be an option for some patients, to help them achieve optimal thyroid replacement.

However, commercially available T3 is only available in limited strengths and only in immediate release form. The immediate release form may result in higher than normal T3 concentrations.

Some research indicates that replacement with compounded sustained release T3 may avoid adverse cardiac effects due to synthetic T3 levels absorbing and rising too rapidly.

Physicians and their patients may wish to consider the inclusion of sustained release T3 in the treatment of low thyroid levels, particularly when the response to T4 has not been complete.

Hazle Compounding specializes in compounding Triiodothyronine (T3) in many different strengths, all in a sustained release form, and customized to each patients individual needs. The T3 capsules are color coded and we also offer a unique T3 starter pak for patients who may be changing strengths as determined by their physician.

Ask our compounding specialists for more information about this exciting therapy option for patients with low thyroid levels.

Hazle Compounding specializes in meeting specific needs...the importance of individualized therapy and the Physician-Pharmasist-Patient Relationship in providing optimal thyroid hormone replacement therapy can not be overemphasized.

We will work together with patient and physician, to develop a customized therapy plan that is best for each patient. All patients are counseled regarding the appropriate use of each medication, potential side effects, and signs that a dosage modification may be necessary.